BACKGROUND - We report a case in which magnetic resonance imaging (MRI) documented the formation of a neurohypophyseal germinoma from its earliest stage. CASE DESCRIPTION - A 9-year-old girl presented with polyuria, polydipsia, and growth retardation. Urinary and endocrinological examination indicated diabetes insipidus (DI) and growth hormone deficiency. No clear evidence of a mass in the hypothalamo-pituitary area was apparent on the first MRI scan. Follow-up MRIs and endocrinological examinations revealed that a tumor, arising from the stalk and posterior lobe of the pituitary gland, formed a mass and caused anterior pituitary function to deteriorate. Histologic diagnosis was germinoma based on open biopsy. CONCLUSION - Radiologic findings in this case indicated the primary site of this intrasellar germinoma to be the hypothalamo-neurohypophyseal region, designating this a 'neurohypophyseal germinoma.' Copyright © 2001 Elsevier Science Inc.
Oishi, M., Morii, K., Okazaki, H., Tamura, T., & Tanaka, R. (2001). Neurohypophyseal germinoma traced from its earliest stage via magnetic resonance imaging: Case report. Surgical Neurology, 56(4), 236–241. https://doi.org/10.1016/S0090-3019(01)00575-4