A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support

Anne Routledge; Mark P. Wallis; Kenneth C. Ross; William Fraser

Journal Article

A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support

Routledge A
Wallis M
Ross K
et al.

Bioorganic and Medicinal Chemistry Letters (1995) 5(18) 2059-2064

DOI: 10.1016/0960-894X(95)00368-4

17Citations

8Readers

Get full text

Abstract

Automated solid phase synthesis of 2′-deoxyribose oligonucleotides; d(Tp)7T, d(Tps)7T and d(Tp)3(CBzp)2(Tp)2T, was achieved directly in 99% overall yields using a novel silyl linkage to a CPG silica support cleavable within seconds at room temperature using TBAF. © 1995.

Cite

CITATION STYLE

APA

Routledge, A., Wallis, M. P., Ross, K. C., & Fraser, W. (1995). A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support. Bioorganic and Medicinal Chemistry Letters, 5(18), 2059–2064. https://doi.org/10.1016/0960-894X(95)00368-4

A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support

Abstract

Cite

Register to see more suggestions