Novel stereoconfiguration in lyso-bis-phosphatidic acid of cultured BHK-cells

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Lyso-bis-phosphatidic acid purified from cultured hamster kidney fibroblast cells (BHK-cells) was subjected to strong alkaline hydrolysis. The hydrolysate contained phosphorus, free glycerol, total glycerol, α-glycerophosphate, β-glycerophosphate and sn-glycerol-3-phosphate in mole ratios of 1.0:1.0:1.9:0.4:0.6:0.02. The absence of sn-glycerol-3-phosphate indicates that the backbone of this lipid has the uncommon structure of 1-sn-glycerophosphoryl-1′-sn-glycerol. Consequently, the biosynthesis and the degradation of this lipid must differ from the other known mammalian glycerophospholipids. © 1974.




Brotherus, J., Renkonen, O., Herrmann, J., & Fischer, W. (1974). Novel stereoconfiguration in lyso-bis-phosphatidic acid of cultured BHK-cells. Chemistry and Physics of Lipids, 13(2), 178–182.

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