A novel type of unsaturated seconucleoside analogues

Abstract

1′,2′-Unsaturated secoadenosine 3-6 and secouridine 15, 16 analogues were synthesized by the base promoted regioselective elimination of corresponding 2′,3′-ditosylates. Efficient and selective O-detritylation of these acid sensitive compounds was achieved by ZnBr2 in dichloromethane. © 1994.