Plate height theory for compressible mobile phase fluids and its application to gas, liquid and supercritical fluid chromatography

Abstract

General expressions for apparent plate height are derived in terms of temporal and spatial average values of local plate height, solute capacity factor and mobile phase density. The general expressions are applied to the appropriate expressions for gas chromatography, liquid chromatography and supercritical fluid chromatography with open tubular and packed columns. For gas chromatography, the equations reduce to the equations presented earlier by Giddings. For liquid chromatography, the equations reduce to those for local plate height. Predicted results for supercritical fluid chromatography are compared to experimental results reported in the literature. © 1990.