Abstract
Reaction of 1-N-alkyl triazoles with an alkyl radical generated from the corresponding carboxylic acid, affords the triazole ring alkylated selectively in the 5 position. Secondary radicals perform best in the intermolecular reaction, while primary radicals alkylate the triazole in an intramolecular fashion. © 2001 Elsevier Science Ltd. All rights reserved.
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CITATION STYLE
APA
Hansen, K. B., Springfield, S. A., Desmond, R., Devine, P. N., Grabowski, E. J. J., & Reider, P. J. (2001). Radical alkylation of N-alkyl 1,2,4-triazoles. Tetrahedron Letters, 42(42), 7353–7355. https://doi.org/10.1016/S0040-4039(01)01518-0
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