Rodent models clarify the role of cells expressing the substance P receptor in pain

1Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The recent failure of substance P receptor (NK1) antagonists in clinical trials for treatment of pain spawned additional studies asking why preclinical models implicating SP in chronic pain did not translate into a viable target for analgesic development. This review focuses on recent pain model system studies, suggesting that it is not SP or NK1 per se, but rather the cells that express NK1 that are crucial for maintaining chronic pain. © 2004 Elsevier Ltd. All rights reserved.

Cite

CITATION STYLE

APA

Carrasquillo, Y., & Gereau IV, R. W. (2004). Rodent models clarify the role of cells expressing the substance P receptor in pain. Drug Discovery Today: Disease Models. Elsevier Ltd. https://doi.org/10.1016/j.ddmod.2004.09.009

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free