Selective O-demethylation during bromination of (3,4-dimethoxyphenyl)(2,3, 4-trimethoxyphenyl)methanone

Abstract

(3,4-Dimethoxyphenyl)(2,3,4-trimethoxyphenyl)methanone was synthesized and its bromination was investigated in different conditions. Nine new products (bromophenol derivatives) were isolated in the reactions. These bromophenol derivatives were obtained by selective O-demethylation in its bromination with bromine. The products and their formations were discussed. © 2011 Published by Elsevier Ltd.