Substance P neurons project from the ventral medulla to the intermediolateral cell column and ventral horn in the rat

  • Helke C
  • Neil J
  • John Massari V
 et al. 
  • 5

    Readers

    Mendeley users who have this article in their library.
  • 161

    Citations

    Citations of this article.

Abstract

The descending substance P projections from the ventral medulla were studied in the rat. Electrolytic lesions which included the nucleus interfascicularis hypoglossi decrease the substance P-like immunoreactivity (SP-I) in both the intermediolateral cell column and the ventral horn of the spinal cord. Lesions of other ventral medullary areas and midbrain hemisections did not change spinal cord SP-I levels. Intracerebroventricular administration of the serotonin neurotoxin, 5,7-dihydroxytryptamine, reduced the SP-I content of the ventral horn but not of the intermediolateral cell colum. © 1982.

Author-supplied keywords

  • intermediolateral cell column
  • raphe nuclei
  • substance P
  • ventral horn of the spinal cord
  • ventral medulla

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Cinda J. Helke

  • Jeffrey J. Neil

  • V. John Massari

  • Arthur D. Loewy

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free