Synthesis of C-3 alkyl analogs of cocaine

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Abstract

The first general stereocontrolled approach to C-3 alkyl analogs of cocaine is described. The route utilized versatile intermediates 2β-hydroxymethyl-3α-cyanotropane and 2β-hydroxymethyl-3β-cyanotropane. © 2001 Elsevier Science Ltd. All rights reserved.

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Deng, S. X., Huang, D. W., & Landry, D. W. (2001). Synthesis of C-3 alkyl analogs of cocaine. Tetrahedron Letters, 42(36), 6259–6261. https://doi.org/10.1016/S0040-4039(01)01254-0

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