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Journal Article

Synthesis of homoallylic oxygenated α-methylene-γ-butyrolactones: a model for preparing biologically active natural lactones

Tetrahedron Letters (2008) 49(40) 5770-5772
DOI: 10.1016/j.tetlet.2008.07.099
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Abstract

In this Letter we describe a 12% overall yield synthesis of a model for homoallylic oxygenated α-methylene-γ-butyrolactones with relative stereochemistry defined by selective hydrogenation with Rh/Al2O3. The synthesis was realized in 9 steps involving simple reactions. © 2008 Elsevier Ltd. All rights reserved.

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Sass, D. C., Oliveira, K. T. de, & Constantino, M. G. (2008). Synthesis of homoallylic oxygenated α-methylene-γ-butyrolactones: a model for preparing biologically active natural lactones. Tetrahedron Letters, 49(40), 5770–5772. https://doi.org/10.1016/j.tetlet.2008.07.099

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