Synthetic studies on reidispongiolide A, an actin-depolymerizing marine macrolide: synthesis of C11-C22 and C23-C35 segments

  • Akiyama S
  • Toriihara E
  • Suzuki K
 et al. 
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Abstract

The C11-C22 and C23-C35 segments 2 and 3 of reidispongiolide A (1), an actin-depolymerizing marine macrolide, were synthesized enantioselectively in 12 steps from (R)-glycidyl trityl ether and in 12 steps from chiral ketone 15, respectively. © 2009 Elsevier Ltd. All rights reserved.

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Authors

  • Satoshi Akiyama

  • Eisuke Toriihara

  • Kazushi Suzuki

  • Toshiaki Teruya

  • Kiyotake Suenaga

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