Synthetic studies on reidispongiolide A, an actin-depolymerizing marine macrolide: synthesis of C11-C22 and C23-C35 segments

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Abstract

The C11-C22 and C23-C35 segments 2 and 3 of reidispongiolide A (1), an actin-depolymerizing marine macrolide, were synthesized enantioselectively in 12 steps from (R)-glycidyl trityl ether and in 12 steps from chiral ketone 15, respectively. © 2009 Elsevier Ltd. All rights reserved.

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Akiyama, S., Toriihara, E., Suzuki, K., Teruya, T., & Suenaga, K. (2009). Synthetic studies on reidispongiolide A, an actin-depolymerizing marine macrolide: synthesis of C11-C22 and C23-C35 segments. Tetrahedron Letters, 50(35), 5012–5014. https://doi.org/10.1016/j.tetlet.2009.06.075

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