Total synthesis of rodgersinol: A survey of the Cu(II)-mediated coupling of ortho-substituted phenols

  • Jung J
  • Jang J
  • Seo S
 et al. 
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Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent, which avoided tedious protection/deprotection sequence. © 2010 Elsevier Ltd. All rights reserved.

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