VIR: A computational tool for analysis of immunoglobulin sequences

  • Almagro J
  • Vargas-Madrazo E
  • Zenteno-Cuevas R
 et al. 
  • 5

    Readers

    Mendeley users who have this article in their library.
  • 12

    Citations

    Citations of this article.

Abstract

In this paper a microcomputer software named VIR (Variable domains of the Immune Receptors) is reported. This package can be used in sequence studies of immunoglobulin variable domains. The main features of the VIR software in the sequences management are: (1) ease of information recovery/extraction from amino acid sequences; and (2) its capability to obtain multiple sequence alignments with predefined characteristics (i.e. specie and/or specificity). As an analytical tool, the VIR package employs such multiple sequence alignments to compute: (1) tables showing amino acid frequencies; (2) three variability indexes; (3) identity matrices; (4) random samples; and (5) sequences with possible canonical structures. Thus the software reported here is proposed as a useful tool to carry out detailed studies of immunoglobulin variable domains. © 1995.

Author-supplied keywords

  • Canonical structures
  • Data bases
  • Pattern recognition
  • Sequence analysis
  • Variability analysis

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free