3-Hydroxypropionaldehyde, an inhibitory metabolite of glycerol fermentation to 1,3-propanediol by enterobacterial species

  • Barbirato F
  • Grivet J
  • Soucaille P
 et al. 
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Abstract

Glycerol fermentation by Enterobacter agglomerans revealed that both growth and 1,3-propanediol production ceased after consumption of about 430 mM glycerol, irrespective of the initial glycerol content. This phenomenon was assigned to the production of 3-hydroxypropionaldehyde, which was identified by proton nuclear magnetic resonance and which showed a bacteriostatic effect. The accumulation during glycerol fermentation was also observed with two other enterobacterial species, i.e., Klebsiella pneumoniae and Citrobacter freundii.

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  • PMID: 8919810
  • PUI: 26114789
  • SGR: 0029917322
  • SCOPUS: 2-s2.0-0029917322
  • ISSN: 00992240

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