A nickel-catalyzed route for direct, anhydride-additive-free deoxygenation of fatty acids to the corresponding olefins has been developed. The transformation is catalyzed by simple nickel salts of the type NiX2 (X = halide, acetate, acetylacetonate), uses PPh3 as a stoichiometric reductant, and exhibits selectivity for generation of linear α-olefin products. The reaction was rendered cocatalytic in PPh3 using 1,1,3,3-tetramethyldisiloxane (TMDS) as terminal reductant for the in situ reduction of OPPh3 and catalytic Cu(OTf)2
CITATION STYLE
John, A., Hillmyer, M. A., & Tolman, W. B. (2017). Anhydride-Additive-Free Nickel-Catalyzed Deoxygenation of Carboxylic Acids to Olefins. Organometallics, 36(3), 506–509. https://doi.org/10.1021/acs.organomet.6b00940
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