Annual acquisition and administration cost of biologic response modifiers per patient with rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing spondylitis

  • M. B
  • G.J. J
  • N. P
 et al. 
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Abstract

Objective: To estimate annual biologic response modifier (BRM) cost per treated patient with rheumatoid arthritis, psoriasis, psoriatic arthritis, and/or ankylosing spondylitis receiving etanercept, abatacept, adalimumab, certolizumab, golimumab, infliximab, rituximab, or ustekinumab. Methods: This was a cohort study of 69,349 commercially insured individuals in a nationwide claims database with one of these conditions that had a claim for one of these BRMs between January 2008 and December 2010 (the index BRM/index date). Cost per treated patient was calculated as the total BRM acquisition and administration cost to the payer in the first year after the index date (including costs of other BRMs after switching) divided by the number of patients who received the index BRM. Etanercept was selected as the reference for comparisons. Results: Etanercept was the most commonly used index BRM (n = 32,298; 47%), followed by adalimumab (n = 20,582; 30%), infliximab (n = 11,157; 16%), abatacept (n = 2633; 4%), rituximab (n = 1359; 2%), golimumab (n = 687;

Author-supplied keywords

  • abatacept
  • adalimumab
  • adult
  • ankylosing spondylitis
  • article
  • billing and claims
  • biological response modifier
  • certolizumab pegol
  • cohort analysis
  • data base
  • drug cost
  • drug utilization
  • etanercept
  • female
  • golimumab
  • human
  • infliximab
  • major clinical study
  • male
  • prescription
  • psoriasis
  • psoriatic arthritis
  • retrospective study
  • rheumatoid arthritis
  • rituximab
  • ustekinumab

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Authors

  • Bonafede M.

  • Joseph G.J.

  • Princic N.

  • Harrison D.J.

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