Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs

  • Zhao G
  • Walsh E
  • Shryock J
 et al. 
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Effects of ranolazine alone and in the presence of phenylephrine (PE) or isoproterenol (ISO) on hemodynamics, coronary blood flow and heart rate (HR) in the absence and presence of hexamethonium (a ganglionic blocker) were studied in conscious dogs. Ranolazine (0.4, 1.2, 3.6, and 6 mg/kg, intravenous) alone caused transient (

Author-supplied keywords

  • antiadrenergic effect
  • conscious dogs
  • coronary blood flow
  • hemodynamics
  • ranolazine

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  • Gong Zhao

  • Erin Walsh

  • John C. Shryock

  • Eric Messina

  • Yuzhi Wu

  • Dewan Zeng

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