Antimicrobial abietane diterpenoids from Plectranthus elegans

  • Dellar J
  • Cole M
  • Waterman P
  • 20


    Mendeley users who have this article in their library.
  • 67


    Citations of this article.


Two novel abietane diterpenoids have been isolated from the aerial material of Plectranthus elegans and identified as 11-hydroxy-12-oxo-7,9(11),13-abietatriene and 7α,11-dihydroxy-12-methoxy-8,11,13-abietatriene. Their structures were determined through rigorous use of spectroscopic methods. Both inhibited spore germination of the fungus Cladosporium cucumerinum, in direct bioautography, at a dose of 1 μg. The new diterpenes also inhibited the growth of Gram-positive bacteria, in the concentration range 10-40 μg ml-1in broth dilution assay. No effect was observed against Gram-negative bacteria. The ecological implications of these findings are discussed. Copyright © 1996 Elsevier Science Ltd. All rights reserved.

Author-supplied keywords

  • Abietane diterpenoids
  • Antibacterial activity
  • Antifugal activity
  • Lamiaceae
  • Plectranthus elegans

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Joanne E. Dellar

  • Michael D. Cole

  • Peter G. Waterman

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free