Is Bariatric Surgery Effective in Reducing Comorbidities and Drug Costs? A Systematic Review and Meta-Analysis

  • Lopes E
  • Souto K
  • Stein A
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The aim of this study was to assess drug use and costs before and after bariatric surgery (BS). A systematic review of the literature was carried out using the MeSH terms obesity, bariatric surgery, and drug costs for searches of 10 electronic databases up to July 2014. Data were extracted from the 11 studies (37,720 patients) that fulfilled the inclusion criteria. Where applicable, data were pooled by meta-analysis. The average number of drugs per patient decreased from 3.9± 1.86 before surgery to 1.75±1.85 after surgery. Mean reduc-tion in total cost of drugs was 49.8 % over a follow-up dura-tion of 6–72 months. BS is effective for the improvement or resolution of comorbidities and significantly reduces drug use and costs.

Author-supplied keywords

  • Bariatric surgery
  • Cost analysis
  • Drug costs
  • Meta-analysis
  • Pharmacoepidemiology

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  • E C Lopes

  • K E P Souto

  • A T Stein

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