Bioengineered kidneys: New sights on a distant horizon

  • Kuppe C
  • Berger K
  • Smeets B
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The need for renal replacement therapy is currently rising at an annually increasing rate. Current treatment options for patients with end-stage kidney disease include dialysis or organ transplantation. Yet, even though transplant survival has increased due to refined immunosuppressive therapy, morbidity remains high because of organ shortage. Here we discuss a recent publication that describes the transplantation of a bioengineered biocompatible kidney from a decellularized organ scaffold, thus possibly providing a solution to both transplant organ shortage and morbidity associated with long-term immunosuppression.

Author-supplied keywords

  • Bioengineered organs
  • Kidney
  • Stem cells
  • Transplantation

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  • Christoph Kuppe

  • Katja Berger

  • Bart Smeets

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