Breast feeding in infancy and arterial endothelial function later in life. The Cardiovascular Risk in Young Finns Study.

  • Jarvisalo M
  • Hutri-Kahonen N
  • Juonala M
 et al. 
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BACKGROUND/OBJECTIVES: Breast feeding in infancy may be associated with reduced cardiovascular morbidity in adulthood. We examined the association between breast feeding in infancy and arterial function and structure in adulthood in a population-based cohort of Finnish adults. SUBJECTS/METHODS: Noninvasive ultrasound was used to measure brachial artery flow-mediated dilatation (FMD), carotid artery intima-media thickness (IMT) and carotid artery compliance (CAC) in 1667 young adults participating in the Cardiovascular Risk in Young Finns Study with data on early nutrition. RESULTS: Maximal FMD was higher in breast-fed men compared to formula-fed men (7.2+/-4.0 vs 5.9+/-3.4%, P=0.029) while no differences were seen between breast-fed and formula-fed women (8.9+/-4.5 vs 8.8+/-5.0%, P=0.84). In men, the multivariable correlates of FMD included the group variable for breast feeding (P=0.014), birth weight (P=0.043), waist circumference (P

Author-supplied keywords

  • Adult
  • Age Factors
  • Birth Weight
  • Blood Pressure
  • Brachial Artery
  • Breast Feeding
  • Carotid Arteries
  • Cholesterol
  • Endothelium, Vascular
  • Female
  • Finland
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Premature Birth
  • Regional Blood Flow
  • Risk Factors
  • Sex Factors
  • Smoking
  • Tunica Intima
  • Tunica Media
  • Vascular Diseases
  • Vasodilation
  • Waist Circumference
  • physiology
  • physiopathology
  • ultrasonography

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  • M J Jarvisalo

  • N Hutri-Kahonen

  • M Juonala

  • V Mikkila

  • L Rasanen

  • T Lehtimaki

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