Comparison of Human to Macaque Uterosacral-Cardinal Ligament Complex and Its Relationship to Pelvic Organ Prolapse

  • Shahryarinejad A
  • Vardy M
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The uterosacral-cardinal ligament complex is thought to be the critical
structure responsible for uterine and apical vaginal support. It is ill
defined and can be difficult to dissect in the cadaver lab and in the
operating room. Even less information is available on the analogous
structures in the monkey model. We present this report to bring together
what little is known to aid in studying this model and pelvic organ
prolapse ( POP), and to point out the need for critical assessment of
this hormone-responsive tissue in the process of drug development.

Author-supplied keywords

  • animal models
  • female reproduction
  • nonhuman primate

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  • Azin Shahryarinejad

  • Michael David Vardy

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