Comparison of two molecular methods for rapid diagnosis of extrapulmonary tuberculosis

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Abstract

Application of real-time PCR for the detection of Mycobacterium tuberculosis enables results to be obtained in about 2 h. A total of 340 nonrespiratory samples were processed using two real-time PCR assay kits: Xpert MTB/RIF and Cobas TaqMan MTB. The sensitivity and specificity of the Xpert assay were 95% and 100%, respectively, compared to 78% and 98% for the Cobas assay. Copyright © 2011, American Society for Microbiology. All Rights Reserved.

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Causse, M., Ruiz, P., Gutiérrez-Aroca, J. B., & Casal, M. (2011). Comparison of two molecular methods for rapid diagnosis of extrapulmonary tuberculosis. Journal of Clinical Microbiology, 49(8), 3065–3067. https://doi.org/10.1128/JCM.00491-11

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