Confocal Microendoscopy with Chromatic Sectioning

  • Lane P
  • Elliott R
  • MacAulay C
  • 14

    Readers

    Mendeley users who have this article in their library.
  • 17

    Citations

    Citations of this article.

Abstract

Placing a spatial light modulator, such as the Texas Instruments Digital Micromirror Device (DMD), in the light path of a microscope enables a variety of novel applications. One application enables reflectance in vivo confocal imaging of cells and tissue structure through a fiber-optic image guide. While multi-wavelength reflectance confocal microendoscopy with optical sectioning is a requirement for a clinically useful device, some form of axial scanning is also necessary. This is readily achieved using a multi-element lens system with some form of mechanical translation, however, this generally results in large probes and high cost. These limitations can be overcome using a two-element GRIN lens system in which the traditionally undesirable chromatic aberration of such a system can be exploited to allow for color-encoded optical sectioning. In our system a wavelength encoding range of 200 nm permits a sectioning range of 40 μm from the tip of the probe into the tissue.

Author-supplied keywords

  • chromatic aberration
  • confocal microscopy
  • microendoscopy

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Pierre M Lane

  • Robert P Elliott

  • Calum E MacAulay

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free