Continuous urine oxygen tension monitoring in patients undergoing cardiac surgery

  • Kainuma M
  • Yamada M
  • Miyake T
  • 1

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

OBJECTIVES: To evaluate the effect of cardiopulmonary bypass (CPB) on urine oxygen tension (PuO2) and to determine whether perioperative PuO2 can predict postoperative renal dysfunction in patients undergoing cardiac surgery. DESIGN: Prospective clinical study. SETTING: A university research laboratory, a university-affiliated hospital. PARTICIPANTS: Ninety-eight consecutive adult patients undergoing coronary artery bypass surgery or valvular surgery. INTERVENTIONS: PuO2 was continuously measured by inserting a polarographic electrode into the urinary tube connected to a Foley catheter. MEASUREMENTS AND MAIN RESULTS: PuO2 was constant before CPB and then progressively decreased after the start of CPB. It partially recovered at weaning from CPB but did not completely return to its original level until the end of surgery. Postoperative serum creatinine concentrations were significantly higher in patients whose PuO2 decreased after CPB, as compared with those whose PuO2 was constant or increased. The amplitude and the rate of recovery in PuO2 after CPB were significantly associated with peak values of postoperative serum creatinine concentrations. CONCLUSIONS: These results suggest the possibility of PuO2 detecting an early stage of renal dysfunction in cardiac surgery, although further studies will be required to substantiate it.

Author-supplied keywords

  • Acute Kidney Injury/*diagnosis
  • Adult
  • Aged
  • Cardiopulmonary Bypass/*adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Oxygen/*urine
  • Prospective Studies

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Authors

  • M Kainuma

  • M Yamada

  • T Miyake

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free