Discrete start sites for DNA synthesis in the yeast ARS1 origin.

  • Bielinsky A
  • Gerbi S
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Sites of DNA synthesis initiation have been detected at the nucleotide level in a yeast origin of bidirectional replication with the use of replication initiation point mapping. The ARS1 origin of Saccharomyces cerevisiae showed a transition from discontinuous to continuous DNA synthesis in an 18-base pair region (nucleotides 828 to 845) from within element B1 toward B2, adjacent to the binding site for the origin recognition complex, the putative initiator protein.

Author-supplied keywords

  • Base Composition
  • Base Sequence
  • Binding Sites
  • DNA Helicases
  • DNA Helicases: metabolism
  • DNA Primers
  • DNA Replication
  • DNA, Fungal
  • DNA, Fungal: biosynthesis
  • DNA-Binding Proteins
  • Molecular Sequence Data
  • Replication Origin
  • Saccharomyces cerevisiae
  • Saccharomyces cerevisiae: metabolism
  • Trans-Activators
  • Trans-Activators: metabolism

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  • a K Bielinsky

  • S a Gerbi

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