Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho

  • Ford N
  • Kranzer K
  • Hilderbrand K
 et al. 
  • 16


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


INTRODUCTION: The latest WHO guidelines recommend initiating antiretroviral therapy (ART) at CD4 cell counts less than 350 cells/mul. However, donors and national governments are reluctant to support implementation owing to uncertainty regarding feasibility and relative benefit. Lesotho has supported earlier initiation since 2008. We assessed outcomes comparing early (CD4 cell counts >200 cells/mul) and late (CD4 cell counts

Author-supplied keywords

  • Adult
  • Antiretroviral Therapy, Highly Active/methods
  • CD4 Lymphocyte Count
  • Drug Administration Schedule
  • Female
  • HIV Infections/*drug therapy/immunology/mortality
  • Humans
  • Lesotho/epidemiology
  • Male
  • Middle Aged
  • Residence Characteristics
  • Viral Load

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in


  • N Ford

  • K Kranzer

  • K Hilderbrand

  • G Jouquet

  • E Goemaere

  • N Vlahakis

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free