Electron microscopy of tobacco mosaic virus under conditions of minimal beam exposure

  • Williams R
  • Fisher H
  • 17

    Readers

    Mendeley users who have this article in their library.
  • 166

    Citations

    Citations of this article.

Abstract

A new technique of electron microscopy has been developed which, when applied to the micrography of tobacco mosaic virus, results in a notably improved delineation of its fine structure. The technique stems from earlier observations that the amount of electron beam irradiation normally used in electron microscopy is destructive to biological specimens. A method is described to minimize such damage, wherein the specimen is subjected only to the irradiation necessary to obtain a photographic exposure. The contrast in the appearance of tobacco mosaic virus as micrographed by the new procedures, and by traditional ones, is demonstrated. © 1970.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Robley C. Williams

  • Harold W. Fisher

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free