The Emerging Architecture of Neuropsychological Impairment in Epilepsy

  • Hermann B
  • Lin J
  • Jones J
 et al. 
  • 62

    Readers

    Mendeley users who have this article in their library.
  • 34

    Citations

    Citations of this article.

Abstract

A new literature is now under way, one linking cognitive abnormalities directly to indices of structural, functional, metabolic, and other neurobiologic markers of cerebral integrity, independent of their association with clinical epilepsy characteristics. These trends are reviewed in this article. The focus is on temporal lobe epilepsy (TLE) as a model with which to address the core points because this form of localization-related epilepsy has been very carefully studied from both a cognitive and imaging standpoint. Some pertinent historical issues are touched on first, followed by more detailed reviews of the cognitive and neuroimaging abnormalities that have been found in TLE, followed by an overview of studies examining direct structure-function relationships in TLE and other epilepsies. © 2009 Elsevier Inc. All rights reserved.

Author-supplied keywords

  • Epilepsy
  • Neuroimaging
  • Neuropsychology
  • Temporal lobe epilepsy
  • White matter

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Bruce P. Hermann

  • Jack J. Lin

  • Jana E. Jones

  • Michael Seidenberg

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free