An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs

  • Clark V
  • Harinantenaina L
  • Zeller M
 et al. 
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The skins of Madagascar poison frogs (Mantella) and certain Neotropical poison frogs (Epipedobates, Dendrobates) secrete the new bile acid tauromantellic acid (1), which was found in both wild-caught and captive-born frogs. This is the first molecule of endogenous origin detected in skin secretions from these taxa. Sucrose was also detected in secretions from wild-caught Mantella but not in captive-born frogs, suggesting a dietary origin.

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