Erectile dysfunction in essential arterial hypertension and effects of sildenafil: results of a {S}panish national study.

  • Aranda P
  • Ruilope L
  • Calvo C
 et al. 
  • 2

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Abstract

B{ACKGROUND}: {T}he aim of this study was to establish the prevalence of erectile dysfunction ({ED}) in hypertensive patients in specialized care hypertension units ({SCHU}s) and to assess the effectiveness and tolerability of sildenafil treatment. {METHODS}: {T}his was a multicenter, prospective, open, observational pharmacoepidemiology study conducted in 25 {S}panish {SCHU}s. {A} total of 2130 men with essential hypertension under treatment were recruited. {I}n a second phase, 291 subjects with a score < or = 21 in the {S}exual {H}ealth {I}nventory for {M}en ({SHIM}) received sildenafil (50 mg/day) as required 30 to 60 minutes before sexual activity, and were evaluated by the {I}nternational {I}ndex of {E}rectile {F}unction ({IIEF}). {RESULTS}: {A} total of 975 subjects (45.8%) had a score < or = 21 in the {SHIM}. {I}n the second phase, sildenafil improved the score in the erectile function domain in 232 patients (83.2%). {S}everity of {ED} significantly improved ({P}

Author-supplied keywords

  • 14751656
  • 3'
  • 5'-Cyclic-GMP Phosphodiesterase
  • Adult
  • Aged
  • Antihypertensive Agents
  • Body Mass Index
  • Headache
  • Humans
  • Hypertension
  • Impotence
  • Male
  • Middle Aged
  • Piperazines
  • Prospective Studies
  • Research Support
  • Treatment Outcome
  • Vasodilator Agents

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Authors

  • Pedro Aranda

  • Luis M Ruilope

  • Carlos Calvo

  • Manuel Luque

  • Antonio Coca

  • Angel Gil de Miguel

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