The axolotl (Ambystoma mexicanum) has been characterized as immunodeficient, and the absence of major histocompatibility complex (MHC) class II polymorphism has been cited as a possible explanation. Here we present evidence for considerable allelic polymorphism at the MHC class II DAB locus for a sample of wild-caught axolotls. Evidence that these sequences are the product of balancing selection for disease resistance is discussed. © 2007 The Authors.
CITATION STYLE
Richman, A. D., Herrera, G., Reynoso, V. H., Méndez, G., & Zambrano, L. (2007). Evidence for balancing selection at the DAB locus in the axolotl, Ambystoma mexicanum. International Journal of Immunogenetics, 34(6), 475–478. https://doi.org/10.1111/j.1744-313X.2007.00721.x
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