Journal of Chromatography B: Biomedical Sciences and Applications, vol. 577, issue 2 (1992) pp. 289-298
We have developed a rapid, simple and precise gas chromatographic headspace analysis for sevoflurane in blood which circumvents problems associated with the high volatility and low blood/gas partition coefficient of this anesthetic drug. Blood standards are easily prepared by volumetric addition of a saturated aqueous solution of sevoflurane. Likewise, internal standardization is achieved using a saturated aqueous solution of halothane. Chromatographic conditions are similar to those commonly used for the analysis of blood ethanol. A simple method is also described for the preparation of stable and precise aliquots of quality control materials for this assay. ?? 1992.
Mendeley saves you time finding and organizing research
Choose a citation style from the tabs below