Improvements in genotyping technologies have led to the increased use of genetic polymorphism for inference about population phenomena, such as migration and selection. Such inference presents a challenge, because polymorphism data reflect a unique, complex, non-repeatable evolutionary history. Traditional analysis methods do not take this into account. A stochastic process known as the 'coalescent' presents a coherent statistical framework for analysis of genetic polymorphisms.
CITATION STYLE
Rosenberg, N. A., & Nordborg, M. (2002). Genealogical trees, coalescent theory and the analysis of genetic polymorphisms. Nature Reviews Genetics. https://doi.org/10.1038/nrg795
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