1,2-Dihydroxyanthraquinone (1) was isolated from the seed of Cassia obtusifolia through bioassay-guided fractionation. 1,2-Dihydroxyanthraquinone strongly inhibited the growth of Clostridium perfringens and Escherichia coli. Structure-activity relationship revealed that 1,4-dihydroxyanthraquinone (2) and 1,8-dihydroxyanthraquinone (3) had strong growth-inhibition against C. perfringens. In growth-promoting activity, 1,2-, 1,4-, and 1,8- dihydroxyanthraquinones exhibited strong growth-promoting activity to Bifidobacterium bifidum. © 2004 Elsevier B.V. All rights reserved.
CITATION STYLE
Sung, B. K., Kim, M. K., Lee, W. H., Lee, D. H., & Lee, H. S. (2004). Growth responses of Cassia obtusifolia toward human intestinal bacteria. Fitoterapia, 75(5), 505–509. https://doi.org/10.1016/j.fitote.2004.03.012
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