Abstract
(Figure Presented) The mercury project: A self-cleaving DNAzyme that "switches on" in the presence of Hg2+ has been revealed by in vitro selection. The enzyme 10-13 (see picture) utilizes two modified nucleobases to confer an RNaseA-like catalytic activity that requires only Hg2+ and no other divalent metal cofactor. This DNAzyme is highly selective for mercuric cations. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
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Hollenstein, M., Hipolito, C., Lam, C., Dietrich, D., & Perrin, D. M. (2008). A highly selective DNAzyme sensor for mercuric ions. Angewandte Chemie - International Edition, 47(23), 4346–4350. https://doi.org/10.1002/anie.200800960
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