Histone acetylation is generally considered a mark involved in activating gene expression by making chromatin structures less compact. In the April 1, 2010, issue of Genes & Development, Xhemalce and Kouzarides (pp. 647-652) demonstrate that the acetylation of histone H3 at Lys 4 (H3K4) plays a role in the formation of repressive heterochromatin in Schizosaccharomyces pombe. H3K4 acetylation mediates a switch of chromodomain proteins associated with methylated H3K9 during heterochromatin assembly. © 2010 by Cold Spring Harbor Laboratory Press.
CITATION STYLE
Kim, J. H., & Workman, J. L. (2010, April 15). Histone acetylation in heterochromatin assembly. Genes and Development. https://doi.org/10.1101/gad.1922110
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