Abstract
The development of a few worldwide routinely used Pt(II) coordination compounds is described from a mechanistic point of view and related to the molecular aspects of Pt-DNA binding. Mechanistic knowledge developed from these studies is applied nowadays for the design and synthesis of new bifunctional and trifunctional compounds, aimed for use as improved anticancer drugs.©2011 IUPAC.
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APA
Reedijk, J. (2011). Increased understanding of platinum anticancer chemistry. Pure and Applied Chemistry, 83(9), 1709–1719. https://doi.org/10.1351/PAC-CON-10-11-03
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