Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography

  • Schroeder S
  • Kopp A
  • Kuettner A
 et al. 
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Abstract

Objectives: Initial reports indicate that coronary artery lesions might be visualized with high sensitivity and specificity by the use of recently introduced multislice computed tomography (MSCT). Current CT technology offers a temporal resolution of 250 ms. In case of heart rates (HRs) >65 beats/min (bpm), however, the reconstruction software switches from a single-phase algorithm (using data from one heart cycle only) to a biphase algorithm using image data of two consecutive heart cycles, improving temporal resolution to down to 125 ms. Thus, it was the aim of the present study to evaluate the influence of the patients' (pts) HR on image quality expressed by vessel segment visibility. Methods and results: MSCT scans (Somatom VZ) were performed in 94 pts. Ten coronary segments were analyzed in each patient with regard to image quality (RCA: segments [sgts] 1–4, LMS: sgt 5, LAD: sgts 5–8, LCX: sgts 11, 12). A total of 697 of 940 (74.1%) sgts were accurately visualizable (RCA: 244/376 [64.9%], LMS: 94/94 [100%], LAD: 232/283 (82.3%), LCX: 146/188 [77.7%]). β-Blocker therapy had a significant influence on mean HR (65 pts on β-blocker, HR 65.1±10.7 bpm vs. 29 pts, HR 71.6±12.2 bpm, P=.01). A significant inverse correlation between HR and segmental visibility was found (r=−.48, P

Author-supplied keywords

  • Cardiovascular imaging
  • Coronary artery disease (CAD)
  • Heart rate
  • Image reconstruction
  • Multislice computed tomography (MSCT)

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Authors

  • Stephen Schroeder

  • Andreas F Kopp

  • Axel Kuettner

  • Christof Burgstahler

  • Christian Herdeg

  • Martin Heuschmid

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