The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease

  • Fernebro J
  • Blomberg C
  • Morfeldt E
 et al. 
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Abstract

Streptococcus pneumoniae is a genetically diverse major human pathogen, yet a common colonizer of the nasopharynx. Here we analyzed the influence of defects affecting in vitro growth rate, on the ability of S. pneumoniae to colonize and to cause invasive disease in vivo.

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Authors

  • Jenny Fernebro

  • Christel Blomberg

  • Eva Morfeldt

  • Hans Wolf-Watz

  • Staffan Normark

  • Birgitta Henriques Normark

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