Meet the corneal myofibroblast: The role of myofibroblast transformation in corneal wound healing and pathology

Abstract

In recent years the role of the myofibroblast in corneal wound healing has been extensively studied. The transformation of the corneal keratocyte to the fibroblast and myofibroblast phenotypes is a critical process in normal and pathologic corneal wound healing. This review will introduce this important transformation and its role in corneal wound healing and pathology. © 2009 American College of Veterinary Ophthalmologists.