Memory Deficit Produced by Bilateral Lesions in the Hippocampal Zone

  • Penfield W
  • Milner B
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It has often been assumed that memory depends upon the total action of the brain rather than upon some specialized intra- cerebral neuron mechanism. There is recent evidence, however, in support of the view that the recording of experience is localiz- able in the same sense that sensory func- tions and speech functions are localizable. Obviously, none of these subdivisions is separable from the work of the brain as a whole. The following study shows that the ca- pacity to record the daily current of con- scious experience may be lost when there is bilateral destruction of a man's hippocam- pus and hippocampal gyrus. Functional paralysis of this recording mechanism does not, however, interfere with the patient's intellectual performance in other psycho- logical tests not dependent on recent mem- ory. Skills, language, and all those things which have already been learned are not lost.

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  • Wilder Penfield

  • Brenda Milner

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