Neural interfaces and implants are finding more clinical applications and there are rapid technological advances for more efficient and safe design, fabrication and materials to establish high-fidelity neural interfaces. In this review paper, we highlight new developments of the microfabricated electrodes and substrates with regard to the design, materials, fabrication and their clinical applications. There is a noticeable trend towards integration of microfluidic modules on a single neural platform. In addition to the microelectrodes for neural recording and stimulation, microfluidic channels are integrated into a nerve-electrode interface to explore the rich neurochemistry present at the neural interface and exploit it for enhanced electrochemical stimulation and recording of the central and peripheral nervous system. © 2013 Copyright Taylor and Francis Group, LLC.
CITATION STYLE
Song, Y. A., Ibrahim, A. M. S., Rabie, A. N., Han, J., & Lin, S. J. (2013). Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering. Biotechnology and Genetic Engineering Reviews, 29(2), 113–134. https://doi.org/10.1080/02648725.2013.801231
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