MIH supplementation strategies: Prospective clinical and laboratory trial

  • Baroni C
  • Marchionni S
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The use of calcium-phosphate casein on hypomineralized molars (molar incisor hypomineralization, MIH) has been proposed but not clinically investigated. Qualitative and quantitative effects of supplementation with a calcium-phosphate casein product on MIH molars were monitored over a period of three years. Molar replicas, minimally invasive biopsies and their SEM microphotographs, plus ESEM/EDX semi-quantitative peaks of elements present in affected enamel were evaluated. Mineralization, morphology, and porosity appeared markedly improved, with calcium and phosphate levels reaching almost normal levels at three years' follow-up. The hypothesis tested was rejected, since calcium-phosphate casein improved enamel morphology in vivo.

Author-supplied keywords

  • mineralized tissue/development
  • pediatric dentistry
  • remineralization
  • scanning electron microscopy (SEM)
  • supportive oral care

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