Postnatal secretion of the subcommissural organ of the Meriones shawi: Control of serotonin innervation

  • Laalaoui A
  • Ahboucha S
  • Didier-Bazes M
 et al. 
  • 4

    Readers

    Mendeley users who have this article in their library.
  • 12

    Citations

    Citations of this article.

Abstract

The postnatal development of the subcommissural organ (SCO) glycoprotein secretion in form of Reissner's fiber and the putative control of the serotonin innervation upon the SCO activity were examined by immunohistochemistry in the semi-desert rodent, Meriones shawi. Abundant SCO secretory material and numerous serotoninergic fibers reaching the SCO were observed in newborns meriones. An increase of both secretory material and serotonin fibres density inside the SCO was observed during postnatal period and into adulthood. Neurotoxic destruction with 5,7-dihydroxytryptamine of the SCO serotonin input in the adult or the inhibition of serotonin synthesis by para-chlorophenylalanine at different postnatal ages, resulted in a decrease of the intensity of SCO Reissner's fiber immunolabelling suggesting a reduction in the SCO secretory material. This result might reflect either an inhibition of the synthesis or a stimulation of release of secretory material. These data suggest that serotonin innervation could be precociously involved in the regulation of the merione SCO secretion. © 2001 Elsevier Science B.V.

Author-supplied keywords

  • Immunohistochemistry
  • Meriones shawi
  • Postnatal development
  • Reissner's fiber
  • Serotonin
  • Subcommissural organ

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Abdelhadi Laalaoui

  • Samir Ahboucha

  • Marianne Didier-Bazes

  • Michelle Fèvre-Montange

  • Annie Meiniel

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free