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Journal article

Predictors and prognosis of refractory status epilepticus treated in a neurological intensive care unit.

Holtkamp M, Othman J, Buchheim K, Meierkord H...(+4 more)

Journal of neurology, neurosurgery, and psychiatry, vol. 76, issue 4 (2005) pp. 534-539

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Abstract

OBJECTIVE: To assess risk factors and prognosis in patients with refractory status epilepticus (RSE). METHODS: We retrospectively analysed all episodes of status epilepticus (SE) treated between 1993 and 2002 on the neurological intensive care unit (NICU) of the Charite-Universitatsmedizin Berlin. The predictive and prognostic features of RSE were compared with non-RSE (NRSE). All patients with "de novo" SE were followed up to identify the possible development of post-SE symptomatic epilepsy. RESULTS: A total of 83 episodes fulfilled our criteria of SE. Of these 43% were refractory to first line anticonvulsants. The mean age of patients with SE was 53.3 (SD 19) years, with only two patients younger than 18 years. Encephalitis was significantly more often the primary cause in RSE (p

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