Presence of Pili on the Surface of Francisella tularensis

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Abstract

Francisella tularensis is a highly infectious gram-negative bacterium with potential for use as a bioweapon. Analysis of the F. tularensis live vaccine strain (LVS) ultrastructure by electron microscopy revealed the presence of long, thin fibers, similar in appearance to type 4 pili. The highly virulent F. tularensis Schu S4 strain was found to contain type 4 pilus genes, and we confirmed that these genes are present and expressed in the LVS.

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Gil, H., Benach, J. L., & Thanassi, D. G. (2004). Presence of Pili on the Surface of Francisella tularensis. Infection and Immunity, 72(5), 3042–3047. https://doi.org/10.1128/IAI.72.5.3042-3047.2004

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