Regio- and stereoselective synthesis of novel dispiropyrrolidine: Bisoxindole derivatives via multicomponent reactions

  • Liu H
  • Dou G
  • Shi D
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A convenient and efficient method for the synthesis of novel dispiropyrrolidine bisoxindole derivatives by 1,3-dipolar cycloaddition reaction of azomethine ylides has been developed. The synthesis was achieved by using a one-pot multicomponent procedure. The features of this procedure were characterized by the following: mild reaction conditions, high yields, high regio- and stereoselectivity, one-pot procedure, and operational simplicity.

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  • Hai Liu

  • Guolan Dou

  • Daqing Shi

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