Regulation of Vascular Reactivity in Scleroderma: New Insights into Raynaud's Phenomenon

  • Flavahan N
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Abstract

Because of the role of the RhoA/Rho kinase (ROCK) pathway in regulating numerous pathologic processes including vasoconstriction, vascular remodeling, and fibrosis, ROCK inhibitors may be especially beneficial in treating Raynaud's phenomenon and scleroderma. 2008 Elsevier Inc. All rights reserved.

Author-supplied keywords

  • blood vessel reactivity blood vessel wall drug mec

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Authors

  • N A Flavahan

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